The σ enigma: Bacterial σ factors, archaeal TFB and eukaryotic TFIIB are homologs

The σ enigma: Bacterial σ factors, archaeal TFB and eukaryotic TFIIB are homologs

Structural comparisons of initiating RNA polymerase complexes and structure-based amino acid sequence alignments of general transcription initiation factors (eukaryotic TFIIB, archaeal TFB and bacterial σ factors) show that these proteins are homologs. TFIIB and TFB each have two-five-helix cyclin-like repeats (CLRs) that include a C-terminal helix-turn-helix (HTH) motif (CLR/HTH domains). Four...

Archaeal and eukaryotic homologs of Hfq

Hfq and other Sm proteins are central in RNA metabolism, forming an evolutionarily conserved family that plays key roles in RNA processing in organisms ranging from archaea to bacteria to human. Sm-based cellular pathways vary in scope from eukaryotic mRNA splicing to bacterial quorum sensing, with at least one step in each of these pathways being mediated by an RNA-associated molecular assembl...

σ-Normality of Topological Spaces

σ-ring and σ-algebra of Sets1

In this article, semi-ring and semi-algebra of sets are formalized so as to construct a measure of a given set in the next step. Although a semi-ring of sets has already been formalized in [12], that is, strictly speaking, a definition of a quasi semi-ring of sets suggested in the last few decades [14]. We adopt a classical definition of a semi-ring of sets here to avoid such a confusion. Ring ...

On effective σ-boundedness and σ-compactness

We prove several dichotomy theorems which extend some known results on σ -bounded and σ -compactpointsets. In particular we show that, given a finite number of Δ1 equivalence relations F1 , . . . , Fn , any Σ1 set A of the Baire space either is covered by compact Δ1 sets and lightface Δ1 equivalence classes of the relations Fi , or A contains a superperfect subset which is pairwise Fi -inequiva...